![]() Council on Thrombosis (in consultation with the Council on Cardiovascular Radiology), American Heart Association. A statement for healthcare professionals. Management of deep vein thrombosis and pulmonary embolism. Thrombolytics and vena caval filters are very rarely indicated in special circumstances.ĭeep vein thrombosis prophylaxis pulmonary embolism treatment venous thromboembolism. These include fondaparinux, a selective indirect factor Xa inhibitor and the new oral selective direct thrombin inhibitors (dabigatran) and selective factor Xa inhibitors (rivaroxaban and apixaban). Currently anticoagulants specifically targeting components of the common pathway have been recommended for prophylaxis. Low-molecular-weight heparin, unfractionated heparin, and vitamin K antagonists have been the treatment of choice. The mainstay of treatment is anticoagulant therapy. Prophylaxis is very important and can be mechanical and pharmacological. The goals of treatment are to prevent extension of thrombi, pulmonary embolism, recurrence of thrombi, and the development of complications such as pulmonary hypertension and post-thrombotic syndrome.ĭVT is a potentially dangerous condition with a myriad of risk factors. Prophylaxis is both mechanical and pharmacological. This will guide further investigations if necessary. The approach to making a diagnosis currently involves an algorithm combining pretest probability, D-dimer testing, and compression ultrasonography. It is predominantly a disease of the elderly and has a slight male preponderance. To present an update on the causes and management of DVT.Ī review of publications obtained from Medline search, medical libraries, and Google.ĭVT affects 0.1% of persons per year. It is a potentially dangerous condition that can lead to preventable morbidity and mortality. It commonly affects the deep leg veins (such as the calf veins, femoral vein, or popliteal vein) or the deep veins of the pelvis. Deep vein thrombosis (DVT) is the formation of blood clots (thrombi) in the deep veins.
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